Chemical design of cilazapril.
نویسندگان
چکیده
منابع مشابه
Cilazapril, Atenolol, Nifedipine
A multicenter, randomized double-blind study of 6 months' duration was performed in 540 patients (average age 54 years, 57% male) with mild-to-moderate essential hypertension to determine the relative effects on quality of life of cilazapril, atenolol, and nifedipine retard. Quality of life was assessed by using both a self-administered and an interviewer-administered questionnaire; the assessm...
متن کاملDoes Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?
In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requires stabilization to ensure safety of its use. The studied CIL/PVP formulations were prepared by ...
متن کاملDoes Polyvinylpyrrolidone Improve the Chemical Stability of Cilazapril in Solid State?
In this study a solid dispersion and a physical mixture of cilazapril (CIL) with a biopolymer - polyvinylpyrrolidone (PVP) as a carrier were prepared so as to investigate the effect of PVP on the stability of CIL. CIL is unstable in solid state and decomposes rapidly under humid conditions. It requires stabilization to ensure safety of its use. The studied CIL/PVP formulations were prepared by ...
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Sir, Cilazapril is a new angiotensin converting enzyme inhibitor (ACEI) which, like other ACEIs, is a non-thiol molecule, containing an active amide group. Since the early 1990s an increasing number of case reports have been published pointing to the role of this family of drugs in inducing or triggering pemphigus (1). In 1992, the ACEI Enalapril was found to be the most powerful acantholytic d...
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deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1989
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1989.tb03474.x